CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers in Sri Lanka
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چکیده
منابع مشابه
Genomic Alterations in Breast Cancer Patients in Betel Quid and Non Betel Quid Chewers
Betel Quid (BQ) chewing independently contributes to oral, hepatic and esophageal carcinomas. Strong association of breast cancer risk with BQ chewing in Northeast Indian population has been reported where this habit is prodigal. We investigated genomic alterations in breast cancer patients with and without BQ chewing exposure. Twenty six BQ chewers (BQC) and 17 non BQ chewer (NBQC) breast canc...
متن کاملMicronuclei (Oral Cancer Biomarker) Study in Buccal Mucosal Cell with Betel Quid Chewers among Indian Population
Oral cancer is most common cancer in males and third most common in females, the main causative agent being use of chewing betel quid (BQ). The micronucleus (MN) assay in exfoliated buccal cells is a useful and minimally invasive method for monitoring genetic damage in humans. Micronuclei (MN) have been proposed as good biomarker to assess cytogenetic damage. MN formation has been observed in c...
متن کاملPrevention of Betel Quid Chewers' Oral Cancer in the Asian-Pacific Area.
"Betel quid chewers' oral cancer" is one of the most common malignancies in South and Southeast Asian countries. Oral premalignancies are also very common in betel quid chewers and about 10% of these undergo malignant transformation. Although education for cessation of the betel quid chewing habit is important, there are few adequate strategies and policies for primary prevention, health promot...
متن کاملComparison of oral Candida species prevalence and carriage among gutka-chewers and betel-quid chewers.
OBJECTIVE To compare prevalence and carriage of Candida species among gutka-chewers and betel-quid-chewers. METHODS The cross-sectional case-control study was conducted between January and December, 2015 at the Oral Surgery department of Abbasi Shaheed Hospital and the Dental department of Jinnah Postgraduate Medical Centre, Karachi, and comprised oral yeast samples of gutka-chewers, betel-qu...
متن کاملIntention to quit betel quid: a comparison of betel quid chewers and cigarette smokers.
BACKGROUND Despite the global significance of betel quid chewing and the associated health risks, there have been no studies assessing chewers' intention to quit. Given the difficulties associated with quitting betel quid and the serious health consequences of chewing, it is important for researchers to develop interventions aimed at helping chewers quit. Betel quid chewers experience similar p...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2002
ISSN: 1460-2180
DOI: 10.1093/carcin/23.4.595